VOC sampling locations table for Ground Zero area, Jan 2002

NYC 9/11 Public Portal Document

Mac Neut 50-1 16 a I I Saline EZS3 MSH -100 ^^ROFA-10 40- ■■■ ROFA -100 12 Ezzzza wTCX-10 30; ESS3WTCX-31.6 ESsaWTCX-lOO 45 8 2 20; I U 4 10- b b 0 0

Eos Lym £==□ Saline [=□ Saline 1,0-1 l.On EZZ3MSH-100 EHHH3MSH-100 ROFA-10 ROFA-10 0.8- ROFA -100 0.8- ■M ROFA - 100 Ezzzza WTCX-10 Ezza WTCX-10 o d-0-6- ESSSS3WTCX-31.6 C 0-6- ESSa WTCX-31.6 Esssa WTCX -100 a BSSaWTCX-lOO wa

S 0.4- §0.4- a 0.2- 0.2-

0.0 0.0 n Figure 6. Experiment A. Bronchoalveolar lavage cell numbers recovered from mice one day after exposure by intratracheal instillation to PM samples in saline or saline vehicle alone. Values shown are means and SEM (n=12 per group). Cell types shown are macrophages and monocytes (Mac), eosinophils (Eos), neutrophils (Neut), and lymphocytes (Lym). “ P < 0.05 vs. Saline group. *’ P < 0.05 vs. Saline group (comparison of rank values) after exclusion ofROFA-100 data which had much larger variances than other groups.

and BAL parameters were determined on day 1. There of the groups of mice, which would be indicated by a were no significant differences in body weights of the slower uptake of CO and a reduced slope (Table 7). These seven groups on day 0 or day 1 (Table 6). Ventilatory data indicate that none of the PM samples caused injury parameters were assessed in mice immediately before and severe enough to significantly reduce gas exchange at the after exposure. There were no differences among groups alveolar-capillary barrier. in breathing frequency, but mice exposed to the 100 pg 3. BAL parameters. Bronchoalveolar lavage dose of ROFA (ROFA-100) had a significant increase in parameters were determined immediately after testing for PenH immediately after exposure in comparison with DLCO. Originally, we planned to do just two sub­ saline control mice (Table 6). There were no significant experiments for this part of Experiment A. However, we changes in immediate responses in mice exposed to any noted that there was significant variation in the total cell dose of WTCX. numbers recovered from the 4 saline control mice in each 2. DLCO. The diffusing capacity of the lung for of sub-experiments Al and A2 (average of 7 x 10'* vs. 33 carbon monoxide was determined 24 hr after X 10'’, respectively). There was no evidence of any oropharyngeal aspiration on groups of 4 mice from the infection (in both cases 99% of BAL cells recovered from same exposure group together in the testing chamber. control mice were alveolar macrophages (AMs)), mice There were no significant differences in DLCO among any came from the same shipment in the same week, and no

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