VOC sampling locations table for Ground Zero area, Jan 2002

NYC 9/11 Public Portal Document

Table 17. Experiment C: Body Weights “ Group Sub­ Body Weight (g) Experiment Day-1 Day 0 Day 1 Day 3 Saline Cl 24.69 24.76 24.72 24.91 0.39 0.42 0.45 0.42 WTC8 Cl 24.76 24.54 24.16 25.35 0.49 0.52 0.58 0.90 WTC13 Cl 24.69 24.26 23.91 24.14 0.40 0.42 0.38 0.43 WTCF Cl 24.72 24.46 24.17 24.41 0.43 0.42 0.38 0.49 NIST Cl 24.75 24.32 24.15 24.31 0.50 0.53 0.50 0.71 Saline C2 nd" 22.55 22.23 22.85 0.27 0.25 0.55 WTCll C2 nd 23.72 23.20 23.72 0.39 0.43 0.68 WTCB C2 nd 23.66 23.11 23.29 0.33 0.33 0.61 WTCC C2 nd 23.67 23.12 23.96 0.27 0.24 0.41 WTCE C2 nd 23.69 23.27 23.44 0.29 0.36 0.41

“ Values shown are means (in bold) and SEM immediately below means (on days -1,0, and 1, n=l 6 per group, except Saline sub-experiment C2: n=8; on day 3, n=8 per group, except Saline sub-experiment C2: n=4). "nd - Not determined. No treatment-related differences in body weight among groups within each sub-experiment were detected.

Responses were examined in 8 mice per group at 1 and 3 or C2 were found. Responsiveness to methacholine days after orophaiyngeal aspiration of 100 pg of each PM aerosol was quantified as PenH AUC (Table 18). Analysis sample or saline alone (n = 4 per time point in sub­ of the data in both sub-experiments showed that linear experiment C2 Saline mice). Responses were examined at regression equations could be fit to the PenH AUC vs. both 1 and 3 day time points in order to begin examination [Meh] data (Figure 15). In both sub-experiments, tests for of persistence of exposure effects. Statistical analysis of equal slopes on days 1 and 3 after exposure showed that the data was performed within each sub-experiment. day was not a significant factor. Therefore, a single Body weights were determined on days -1 (before equation was fit to the data for each group, and day does oropharyngeal aspiration), 0, 1, and 3 in sub-experiment not appear in the equations. Cl, and on days 0, 1, and 3 in sub-experiment C2 (Table In sub-experiment Cl, the WTC8, WTCF, and NIST 17). No treatment-related differences in body weight groups could be described with a common slope and among groups within each sub-experiment were detected, intercept. The common slope of these 3 groups was although there were differences on the day the animals significantly different from and greater than that of the were weighed (P = 0.0001). WTC13 or Saline Cl groups {P < 0.0005), indicating that 2. Responsiveness to methacholine aerosoL In sub­ WTC8, WTCF, and NIST were hyperresponsive to experiment Cl, the WTC8 group had significantly greater methacholine aerosol. The slope of the WTC13 group was baseline PenH values 1- day after exposure compared with significantly greater than that of the Saline Cl group, the WTC13 group (Table 18). No other significant showing that WTC 13 mice were hyperresponsive differences in baseline PenH values in sub-experiments C1 compared with control mice, though less so than WTC8,

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