VOC sampling locations table for Ground Zero area, Jan 2002

NYC 9/11 Public Portal Document

Table 12. Experiment B: Immediate Airway Responses “ Group Breathing Frequency fmin~'1 PenH (unitlessl Pre- Post- % increase Pre- Post- % increase Air 549.2 357.7 -35.0 0.88 1.09 29.5 9.1 24.4 4.1 0.05 0.09 13.8 WTC3 560.3 389.3 -30.1 0.94 1.47 60.1 10.3 19.0 3.9 0.06 0.16 18.2 “ Values shown are means (in bold) and SEM immediately below means (n=12). Respiratory parameters were measured immediately before (Pre-) and after (Post-) nose-only inhalation exposure on day 0. No significant differences in percent change in fi’equency or PenH between groups were found.

2. Body weights. Animal weights were monitored on 3. Immediate airway responses to nose-only days -1 (before exposure), 0 (both before and after exposure. Ventilatory parameters were measured in 12 exposure), 1, 3, and 6 (Table 11). Body weight was mice from each group before and after the nose-only measured between 7:00 and 8:00 each morning, except exposure. Ventilatory rate decreased after exposure in immediately after exposure. There were no significant both groups but there was no significant difference differences between the two groups at any time point. The between them (Table 12). It should be noted that many nose-only exposure caused a significant 2 g drop in body physiological responses are readily reversible, and the time weight in both groups of mice (Figure 10). required to unload the mice from the exposure tubes and

Air WTC3 2.5n 2.51

113 —161 2.0- 114 2.0- —A— 162 115 —163 CZ5 116 CZ3 —164 W lya 117 —165 •= 1.5- 1.5- J : * 118 129 —177 166

S ■ 130 i ■ —A— 178 8 Ph 1.0- —131a § 1.0- Ph —179 —0—132 —0— 180 —O— 133 —O— 181 —1—134 —t— 182 0.5- 0.5-

0.0 T 0.0 Pre- Post- Pre- Post- Figure 11. Experiment B. PenH values measured immediately before and after nose-only exposure to WTC 3 PM or Air only. Legends refer to individual mouse numbers. Immediate response (calculated as [(Post-value - Pre-value) / Pre-value x 100%] was not significantly different between the two groups but data indicate the possibility of individual sensitivity to dust exposure.

26

NYC-WTC_000149169